Bruschi is of Filipino and Italian descent. He is an accomplished saxophonist and has played with the Boston Pops. Bruschi resides in North Attleboro, MA with his wife, Heidi, and their three sons Tedy Jr., Rex and Dante.
In 2007 Bruschi wrote a book about his experience with his stroke and his recovery, entitled Never Give Up: My Stroke, My Recovery, and My Return to the NFL.
In his memoir, Bruschi speaks with candor about how his family confronted the reality of his life-threatening affliction, of his initial plans to retire from the NFL, and of the moment he told his wife he was ready to return to football, earning him a share of the Comeback Player of the Year Award and full ownership of the prestigious Ed Block Courage Award. His book was published by John Wiley & Sons in August 2007.